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Xuefei Ma, Wei Zhang, Rong Zhang, Jingming Li, Shufen Li, Yunlin Ma, Wen Jin, Kankan Wang
Frontiers of Medicine 2019, Volume 13, Issue 3, Pages 330-343 doi: 10.1007/s11684-017-0557-0
Keywords: long noncoding RNA CRNDE alternative splicing
Long noncoding RNA LOC646029 functions as a ceRNA to suppress ovarian cancer progression through the
Frontiers of Medicine Pages 924-938 doi: 10.1007/s11684-023-1004-z
Keywords: ovarian cancer lncRNA LOC646029 metastasis microRNA 627-3p SPRED1
Frontiers of Medicine 2022, Volume 16, Issue 2, Pages 176-184 doi: 10.1007/s11684-021-0885-y
Keywords: small noncoding RNAs epigenetic inheritance paternal intergenerational inherence extracellular vesicles
Noncoding RNAs and Their Potential Therapeutic Applications in Tissue Engineering
Shiying Li, Tianmei Qian, Xinghui Wang, Jie Liu, Xiaosong Gu
Engineering 2017, Volume 3, Issue 1, Pages 3-15 doi: 10.1016/J.ENG.2017.01.005
Keywords: Tissue engineering Noncoding RNAs MicroRNAs Nerve Skin Liver Vascular system Muscle
Nan Ding,Jiafei Xi,Yanming Li,Xiaoyan Xie,Jian Shi,Zhaojun Zhang,Yanhua Li,Fang Fang,Sihan Wang,Wen Yue,Xuetao Pei,Xiangdong Fang
Frontiers of Medicine 2016, Volume 10, Issue 3, Pages 297-310 doi: 10.1007/s11684-016-0452-0
Keywords: erythroid differentiation hematopoietic stem cell RNA-seq miRNA lncRNA
Jing Ma, Shiyu Chen, Lili Hao, Wei Sheng, Weicheng Chen, Xiaojing Ma, Bowen Zhang, Duan Ma, Guoying Huang
Frontiers of Medicine 2021, Volume 15, Issue 1, Pages 91-100 doi: 10.1007/s11684-020-0778-5
Keywords: congenital heart disease Gene Expression Omnibus lncRNA SAP30-2:1 cell proliferation RNA immunoprecipitation
Changes in lncRNAs and related genes in β-thalassemia minor and β-thalassemia major
Jing Ma,Fei Liu,Xin Du,Duan Ma,Likuan Xiong
Frontiers of Medicine 2017, Volume 11, Issue 1, Pages 74-86 doi: 10.1007/s11684-017-0503-1
Keywords: β-thalassemia long non-coding RNA mRNA phenotypic heterogeneity pathway
Ribozyme and the mechanisms that underlie RNA catalysis
Timothy J. Wilson,Yijin Liu,David M. J. Lilley
Frontiers of Chemical Science and Engineering 2016, Volume 10, Issue 2, Pages 178-185 doi: 10.1007/s11705-016-1558-2
Keywords: RNA catalysis RNA structure catalytic mechanism
Anti RNA Viruses Related Biomaterials
Yao Kangde,Yin Yuji,Zhang Baolian,Zhao Liguo
Strategic Study of CAE 2003, Volume 5, Issue 7, Pages 17-23
The structure, reproduction, replication and transcription of RNA viruses were introduced.Antivirus strategies including design of anti - SARS drugs, RNA interference, DNA vaccine delivery systemThese examples imply the interactions of RNA viruses with proteins, DNA, and polysaccharides.
Keywords: Anti-RNA viruses protein DNA polysaccharide biomaterials
RNA-Based Biocontrols—A New Paradigm in Crop Protection Review
Matthew Bramlett, Geert Plaetinck, Peter Maienfisch
Engineering 2020, Volume 6, Issue 5, Pages 522-527 doi: 10.1016/j.eng.2019.09.008
Keywords: RNA-based biocontrols RNA interference (RNAi) Colorado potato beetle (CPB) Corn rootworm (CRW) Soy
Knockdown of a Specific Circular Non-coding RNA Significantly Suppresses Osteosarcoma Progression Article
Shidong Wang, Hongliang Zhang, Bo Li, Chenglong Chen, Tingting Ren, Yi Huang, Kai Liu, Jingjing Li, Wei Guo
Engineering 2023, Volume 21, Issue 2, Pages 187-193 doi: 10.1016/j.eng.2021.12.007
Osteosarcoma (OS) is a malignant mesenchymal tissue tumor known to occur in children and adolescents, and pulmonary metastasis often leads to death in these patients. The mechanism underlying OS progression remains unclear. Therefore, identifying new therapeutic targets and treatment modalities for OS is urgently needed. Abnormally expressed non-coding circular RNAs (circRNAs) are crucial for the occurrence and development of OS. The purpose of this study was to explore the expression and role of a novel circRNA circ_000203 in OS and elucidate the underlying mechanism. circ_000203 was demonstrated highly expressed in OS cell lines and tissues, and circ_000203 knockdown significantly inhibited OS progression in vitro and in vivo. Furthermore, we found that circ_000203 is a sponge of miR-26b-5p, an upstream regulator of bone morphogenetic protein receptor 2 (BMPR2). Thus, the overexpression of BMPR2 could reduce the inhibitory effect on OS progression. This indicates that knockdown of circ_000203 suppresses OS progression through microRNA (miRNA)-mediated BMPR2 downregulation. Our findings provide important insights for understanding the occurrence and development of OS.
Keywords: Non-coding RNA Osteosarcoma CircRNA Molecular mechanism Knockdown
Blockage of receptor-interacting protein 2 expression by small interfering RNA in murine macrophages
LIU Hongchun, CAO Zhongwei, JIN Jianjun, WANG Jiyao
Frontiers of Medicine 2008, Volume 2, Issue 2, Pages 166-170 doi: 10.1007/s11684-008-0030-1
The critical importance of epigenetics in autoimmune-related skin diseases
Frontiers of Medicine 2023, Volume 17, Issue 1, Pages 43-57 doi: 10.1007/s11684-022-0980-8
Keywords: epigenetics autoimmune-related skin diseases DNA methylation histone modifications noncoding RNAs
Fengmin Lu, Jie Wang, Xiangmei Chen, Dongping Xu, Ningshao Xia
Frontiers of Medicine 2017, Volume 11, Issue 4, Pages 502-508 doi: 10.1007/s11684-017-0590-z
Keywords: chronic hepatitis B serum HBV RNA nucleos(t)ide analogs virological response para-functional cure
Frontiers of Medicine doi: 10.1007/s11684-023-1017-7
Keywords: single-cell RNA-seq glioma radial glia primitive oligodendrocyte precursor cell immune escape
Title Author Date Type Operation
Overexpressed long noncoding RNA CRNDE with distinct alternatively spliced isoforms in multiple cancers
Xuefei Ma, Wei Zhang, Rong Zhang, Jingming Li, Shufen Li, Yunlin Ma, Wen Jin, Kankan Wang
Journal Article
Long noncoding RNA LOC646029 functions as a ceRNA to suppress ovarian cancer progression through the
Journal Article
Paternal environmental exposure-induced spermatozoal small noncoding RNA alteration meditates the intergenerational
Journal Article
Noncoding RNAs and Their Potential Therapeutic Applications in Tissue Engineering
Shiying Li, Tianmei Qian, Xinghui Wang, Jie Liu, Xiaosong Gu
Journal Article
Global transcriptome analysis for identification of interactions between coding and noncoding RNAs during
Nan Ding,Jiafei Xi,Yanming Li,Xiaoyan Xie,Jian Shi,Zhaojun Zhang,Yanhua Li,Fang Fang,Sihan Wang,Wen Yue,Xuetao Pei,Xiangdong Fang
Journal Article
Long non-coding RNA SAP30-2:1 is downregulated in congenital heart disease and regulates cell proliferation
Jing Ma, Shiyu Chen, Lili Hao, Wei Sheng, Weicheng Chen, Xiaojing Ma, Bowen Zhang, Duan Ma, Guoying Huang
Journal Article
Changes in lncRNAs and related genes in β-thalassemia minor and β-thalassemia major
Jing Ma,Fei Liu,Xin Du,Duan Ma,Likuan Xiong
Journal Article
Ribozyme and the mechanisms that underlie RNA catalysis
Timothy J. Wilson,Yijin Liu,David M. J. Lilley
Journal Article
RNA-Based Biocontrols—A New Paradigm in Crop Protection
Matthew Bramlett, Geert Plaetinck, Peter Maienfisch
Journal Article
Knockdown of a Specific Circular Non-coding RNA Significantly Suppresses Osteosarcoma Progression
Shidong Wang, Hongliang Zhang, Bo Li, Chenglong Chen, Tingting Ren, Yi Huang, Kai Liu, Jingjing Li, Wei Guo
Journal Article
Blockage of receptor-interacting protein 2 expression by small interfering RNA in murine macrophages
LIU Hongchun, CAO Zhongwei, JIN Jianjun, WANG Jiyao
Journal Article
Potential use of serum HBV RNA in antiviral therapy for chronic hepatitis B in the era of nucleos(t)ide
Fengmin Lu, Jie Wang, Xiangmei Chen, Dongping Xu, Ningshao Xia
Journal Article